Cancer treatment trends

Cancer treatment trends

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Cancer drug 'like taking Panadol' developed in Australia, given fast-track approval in US
ABC
An Australian drug that melts away cancer in some stage four patients is given fast-track approval in the United States, but Australian patients cannot yet access it.
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Immunotherapy cancer drug hailed as 'game changer'
BBC
An immunotherapy drug is described as a potential "game changer" in promising trial results on advanced cancers.
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Scientists claim 'extraordinary' success with treatment using immune cells to target cancer
Fox News
Early trials of a potential cancer treatment in which white blood cells are modified to target certain types of the disease have been an "extraordinary" success, scientists said Monday.
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CRISPR kills HIV and eats Zika 'like Pac-man'. Its next target? Cancer
Wired
CRISPR proteins used with a process that amplifies RNA could be used to detect cancer cells
Signals
Microsoft enters race to find cancer cure
Digital Journal
As Digital Journal has recently reported Microsoft has recently launched Healthcare NeXT, which is a cloud-based, artificial intelligence and research
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Chemotherapy-free 'cancer vaccine' moves from mice to human trials at Stanford
SF Gate
A recent Stanford cancer study that cured 97 percent of mice from tumors has now moved on...
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'Holy grail of cancer research': doctors positive about early detection blood test
The Guardian
Blood tests called liquid biopsies show signs of finding cancers at an early stage
Signals
Brain cancer vaccine could extend lives of patients by years
The Guardian
Trial on people with form of disease that killed Tessa Jowell remarkably promising
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Cancer has a new enemy: A.I.
Popular Mechanics
Microsoft and the giants of cancer research are proving that big data is a mighty weapon.
Signals
Scientists test new anti-PD-L1 cancer vaccine against melanoma
Drug Target Review
An experimental cancer vaccine that boosts the immune system's ability to fight cancers could work in tandem with other cancer therapies
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Cervical cancer set to be eliminated from Australia in global first
The Age
Thanks to world-leading vaccine and screening programs, cervical cancer could be almost unheard of in Australia in coming decades, new research has revealed.
Signals
Bacterial injections into tumors show early promise for treating cancer
Science Magazine
Modern update of once-controversial approach helps a handful of patients
Signals
Early clinical trials showing promise for new kind of cancer vaccine
New Atlas
Promising early results are in from a phase 1 clinical trial into a new cancer vaccine designed to stimulate the immune system into attacking certain cancers known to overexpress a specific protein.
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Four new technologies that will change cancer treatment
Labiotech
New approaches to tame the immune system in the fight against cancer are getting us closer to a future where cancer becomes a curable disease. I spoke with experts in the field to gather a realistic overview of the potential of four of these promising new cancer treatments.
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A cure for cancer: how to kill a killer
The Guardian
Revolutionary work on the body’s immune system and a host of new drug trials mean that beating cancer may be achievable
Signals
Scientists may have found how to treat cancer without chemotherapy by mimicking our body's own self-destruct system
Business Insider
US scientists recently discovered a genetic "kill code" in our cells that could theoretically be used to treat cancer without chemotherapy.
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This new test could detect all types of cancer in just minutes
Science Alert

Researchers have developed a test that could be used to diagnose all cancers. It is based on a unique DNA signature that appears to be common across cancer types.
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Regeneron records 80% complete response rate in lymphoma trial
Fierce Biotech
Regeneron’s CD20xCD3 bispecific antibody has achieved an 80% complete response rate in a small trial of patients with relapsed or refractory follicular lymphoma. The strong early signs of efficacy led Regeneron to target a 2019 start date for a potentially registrational phase 2 study.
Signals
The FDA just approved a drug that targets cancers based on DNA, rather than where the tumor is in your body
Business Insider
The FDA just approved a new cancer treatment in an unconventional way: not by tumor type, but rather by the genetic mutation the drug targets.
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In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment
Nature
Cancer recurrence after surgical resection remains a significant cause of treatment failure. Here, we have developed an in situ formed immunotherapeutic bioresponsive gel that controls both local tumour recurrence after surgery and development of distant tumours. Briefly, calcium carbonate nanoparticles pre-loaded with the anti-CD47 antibody are encapsulated in the fibrin gel and scavenge H+ in th
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Pediatric leukemia ‘super drug’ could be developed in the coming years
University of Northwestern
Fourth study published over two-year span that analyzes key leukemia protein
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Breast cancer cells can be transformed into fat cells using combination therapy, study shows
Pharmafile
Pharmafile.com is a leading portal for the pharmaceutical industry, providing industry professionals with pharma news, jobs, events, and service company listings.
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High response rates for T-VEC in early metastatic melanoma (stage IIIB/C-IVM1a)
NCBI
Talimogene laherparepvec (T-VEC) is a modified herpes simplex virus, type 1 (HSV-1), which can be administered intralesionally in patients with stage IIIB/C-IVM1a unresectable melanoma (EMA label). The phase 3 OPTiM registration study showed an overall response rate (ORR) of 26%. Since December 2016 …
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Cancer ‘vaccine’ shows promise in human trial of lymphoma patients
CNBC
The treatment "has broad implications for multiple types of cancer," said lead author Dr. Joshua Brody.
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Researchers develop breakthrough process to create cancer-killing drugs
Eurekalert
A new strategy for drug development can be used to produce targeted therapies against a variety of diseases.
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Improving cancer treatment is 'major priority' for public
Eurekalert
Enhancing cancer treatment is a 'major priority' for the UK public, which also thinks that the NHS needs more resources to provide 'excellent cancer care,' finds a new national survey led by UCL.
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The two technologies changing the future of cancer treatment
The Atlantic
Researchers are eager to leave behind the brutal side effects of chemotherapy and radiation.  
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'Trojan horse' anticancer drug disguises itself as fat
Eurekalert
A stealthy new drug-delivery system disguises chemotherapeutics as fat in order to outsmart, penetrate and destroy tumors. Thinking the drugs are tasty fats, tumors invite the drug inside. Once there, the targeted drug activates, immediately suppressing tumor growth.
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Aggressive brain cancer treatment: Ohio students’ research shows promise
Medical Daily
This article was removed because it did not meet Medical Daily's editorial standards.
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Alzheimer's breakthrough as scientists find first drug to slow down the disease
The Telegraph
A drug that can slow down the progression of Alzheimer’s disease has finally been found, scientists have announced.
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Cancer death rate in U.S. sees sharpest one-year drop
The New York Times
Breakthrough treatments for lung cancer and melanoma have driven down cancer mortality overall — and from 2016 to 2017 spurred the largest-ever decline.
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Immune cell that kills most cancers discovered by accident by British scientists
The Telegraph
A new type of immune cell which kills most cancers has been discovered by accident by British scientists, in a finding which could herald a major breakthrough in treatment.
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New blood test can detect 50 types of cancer
The Guardian
System uses machine learning to offer new way to screen for hard to detect cancers
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How scientists built a ‘living drug’ to beat cancer
Wired
Researchers didn’t know if it would work, but they had little to lose when they tried a new drug known as a CAR-T—a living cell reprogrammed to recognize and kill leukemia—on a dying 6-year-old.
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Experimental blood test detects cancer up to four years before symptoms appear
https://www.scientificamerican.com/article/experimental-blood-test-detects-cancer-up-to-four-years-before-symptoms-appear/
The assay looks for stomach, esophageal, colorectal, lung and liver malignancies
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Why a promising, potent cancer therapy isn't used in the US
Wired
Carbon ion radiation therapy is being used to blast tumors all over the world. Just not in the country that invented it.
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A.I. making a difference in cancer care
CBS
The artificial intelligence we see in daily life is just a fraction of its vast potential. Already it's making strides in cancer care
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New cancer drug could help people with heart problems
STV News
Aberdeen University researchers made the discovery during pre-clinical trials.
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AI approach outperformed human experts in identifying cervical precancer
NIH
An AI algorithm outperformed other screening methods in identifying cervical precancer. The approach could be especially valuable in low-resource settings.
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Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA
Annals of Oncology
Early cancer detection could identify tumors at a time when outcomes are superior
and treatment is less morbid. This prospective case-control sub-study (from NCT02889978
and NCT03085888) assessed the performance of targeted methylation analysis of circulating
cell-free DNA (cfDNA) to detect and localize multiple cancer types across all stages
at high specificity.
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Annual Report to the Nation: Overall cancer mortality continues to decline
NIH
Special section on adults ages 20 to 49 shows higher cancer incidence and mortality for women than men.
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Researchers identified a connection between viruses and cancer?
Healthfoodis
Seneca Valley virus, named Senecavirus, impacts cows and pigs. Discovered to be capable to uniquely attack human cancer tissues.
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Dose characterization of the investigational anticancer drug Tigilanol Tiglate (EBC-46) in the local treatment of canine mast cell tumors
Frontiers
Mast cell tumor (MCT) is the most common cutaneous neoplasm in dogs and wide surgical resection is the current first-line treatment. However, recurrence is common and often requires more specialist and expensive therapies. Tigilanol tiglate is a novel small molecule drug delivered by intratumoral injection that is currently under development to provide a new option for treating MCT. The aim of thi
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China develops infrared light to alter genes of cancer cells
Asia Times
Chinese scientists claim they have developed an infrared light-based, remotely-controlled gene-editing tool that can target and kill cancer cells with
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Singapore scientists discover new cancer drug that could be alternative to chemotherapy
CNA
SINGAPORE: Singapore scientists have discovered a new antibody drug that could potentially be used as an alternative for chemotherapy in ...
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Liquid biopsies to detect cancer could boost annual sequencing volume by 40-fold
Ark Invest
Liquid biopsies could be the reason that next generation sequencing volumes will scale from 2.4 million in 2018 to 100 million genome-equivalents per year.
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First marker for mysterious vaping illness identified
University of Utah Health
University of Utah Health investigators have identified a previously unrecognized characteristic of a mysterious vaping-related respiratory illness that could allow doctors to definitively diagnose the nascent syndrome more quickly and provide clues into causes of the condition.
Signals
Ultrasound destroys 80 percent of prostate cancers in one-year study
New Atlas
A safer and less invasive treatment option for prostate cancer could soon be on the table, with a novel MRI-guided ultrasound technique eliminating significant cancers in 80 percent of subjects in a year-long study.
Signals
Scientists discover molecule that destroys pancreatic cancer cells
Israel21c
Israeli breakthrough study shows 90% reduction of pancreatic cancer cells in mice after treatment with a molecule named PJ34.
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New cancer treatment delivers weeks of radiation therapy in a second
New Atlas
Radiation therapy is currently our best shot at treating cancer, but healthy cells often become unfortunate collateral damage. New research shows how the treatment can be made safer by reducing the time involved from weeks to seconds.
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The 5 revolutions in cancer treatment
YouTube - a16z
We are at the beginning of a new era for how we treat one of humankind’s oldest and worst foes—cancer. In this talk, Jonathan Lim, CEO and cofounder of Erasc...
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Immunotherapy and the race to cure cancer with Charles Graeber
YouTube - ARK Invest
Today's guest is Charles Graeber (@charlesgraeber), author of the book The Breakthrough: Immunotherapy and the Race to Cure Cancer. Charles tells us about th...
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Making cancer as harmless as the common cold | Michio Kaku
YouTube - Big Think
Making cancer as harmless as the common coldNew videos DAILY: https://bigth.inkJoin Big Think Edge for exclusive video lessons from top thinkers and doers: h...
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Cancer breakthroughs
Charlie Rose
On breakthroughs in cancer treatment, with Drs. Bill Nelson, Louise Perkins, and Neil Segal, and researcher Tom Marsilje.
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Synthetic biology used to target cancer cells while sparing healthy tissue
Stanford University
Stanford researchers have developed synthetic proteins that can rewire cancer cells in a lab dish by co-opting critical disease-associated pathways.
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Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer
Nature
The Zero Childhood Cancer Program is a precision medicine program to benefit children with poor-outcome, rare, relapsed or refractory cancer. Using tumor and germline whole genome sequencing (WGS) and RNA sequencing (RNAseq) across 252 tumors from high-risk pediatric patients with cancer, we identified 968 reportable molecular aberrations (39.9% in WGS and RNAseq, 35.1% in WGS only and 25.0% in RN
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New ‘intelligent’ NHS health checks to be driven by predictive analytics
Digital Health
The Government has launched a review to explore how data and technology can deliver a new era of intelligent, predictive and personalised NHS health checks.
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Suspended animation induced in humans for the first time
CNET
Rapidly cooling patients could buy surgeons extra time to repair traumatic injuries.