Isbeddellada horumarinta tignoolajiyada Crispr
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banki
Barootiinada CRISPR ee loo isticmaalo habka kor u qaadaya RNA waxa loo isticmaali karaa in lagu ogaado unugyada kansarka
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Wargeyska New England Journal of Medicine
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Futurismka
Cilmi-nafsiga Ruushka Denis Rebrikov ayaa sheegay inuu helay shan lammaane oo doonaya inuu isticmaalo CRISPR si loo hubiyo in carruurtoodu aanay dhaxlin dhego-la'aantooda.
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Dib u eegida tiknoolajiyada MIT
Qalabka awooda badan ee wax ka beddelka hidda-wadaha CRISPR ma caawin karaa daaweynta cudurrada? Shirkadaha dawooyinka ayaa ku tartamaya inay ogaadaan. Dhowaan lagu dhawaaqay $300 milyan oo ay iska kaashadeen Bayer AG iyo bilowga CRISPR Therapeutics-si loo horumariyo dawooyin cusub oo loogu talagalay cudurrada dhiigga, indho la'aanta, iyo cudurrada wadnaha ee lagu dhasho - waa calaamaddii ugu dambeysay ee in warshadaha dawooyinka ay u heellan yihiin inay helaan oo ay horumariyaan…
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Cornell Chronicle
Cilmi-baaraha Cornell, oo hormuud u ah horumarinta nooc cusub oo ah habka tafatirka hidda-socodka ee CRISPR, iyo asxaabtiisuba waxay isticmaaleen habka cusub markii ugu horreysay ee unugyada bini'aadamka - horumar weyn oo berrinka ah.
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Nature
Saddex daraasadood oo muujinaya tirtiridda DNA-da waaweyn iyo dib-u-habaynta ayaa kor u qaadaysa welwelka badbaadada ee ku saabsan tafatirka genome-ga la iska dhaxlo. Saddex daraasadood oo muujinaya tirtiridda DNA-da waaweyn iyo dib-u-habaynta ayaa kor u qaadaysa welwelka badbaadada ee ku saabsan tafatirka genome-ga la iska dhaxlo.
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Jirka
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banki
Tessera Therapeutics waxay horumarinaysaa heer cusub oo tafatirayaasha hidda-wadaha oo awood u leh inay si sax ah ugu xidhaan fidsanaanta DNA-da-wax aanay Crispr samayn karin.
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New saynisyahanka
Laba qof oo qaba beta thalassaemia iyo mid qaba cudurka sickle cell uma baahna in dhiig lagu shubo ka dib markii unugyada stem ee dhiigooda la tafatiray oo dib loogu celiyay jirkooda.
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New Atlas
Horumar cusub oo cajiib ah oo ka yimid saynisyahano ETH Zurich ayaa, markii ugu horeysay, soo bandhigay hab cusub oo CRISPR ah kaas oo wax ka beddeli kara daraasiin hiddo-sideyaal isku mar ah, taas oo u oggolaanaysa dib-u-habayn ballaaran oo unugyo ah.
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Hub keli ah
Shiinuhu waxa uu qarax ku arkayaa daraasaadka xayawaanka ee CRISPR-ku-salaysan oo ku qaabilaya tignoolajiyada wax-ka-beddelka hidda-wadaha oo leh xamaasad aan la qiyaasi karin.
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Nature
Walxaha hidde-sideyaasha noolaha ah ee loo yaqaanno transposons waxay wataan mashiinnada CRISPR ee sida caadiga ah ay u isticmaalaan unugyada bakteeriyada. Isbarbardhiggan hadda waa la sharraxay, iyada oo saameyn ku leh cilmi-baarista hidde-therapy. RNA-ku hagayo gudbinta DNA-da.
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Nature
Nidaamyada CRISPR ee caadiga ah waxay ilaaliyaan daacadnimada genomic iyaga oo ka faa'iidaysanaya hagaha RNA-yada nukleaaska-ku-tiirsanaanta nabaad-guurka ee walxaha hidde-socodka guurguura, oo ay ku jiraan plasmids iyo fayrasyada. Halkan waxaan ku sifeyneynaa rogaal-celin caan ah oo ku saabsan jaantuskan, kaas oo bakteeriyada Tn7-sida transposons ay iska kaashadeen Nuclease-la'aanta CRISPR & # XNUMX; Nidaamyada Cas si ay u kiciyaan is dhexgalka RNA-gu hagayo ee unugyada hidde-socodka guurguura
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Hub keli ah
Ujeedadu maaha in la huriyo cabsida dadweynaha ee qalabka; Laakiin waa in aad hore u sii eegto khataraha iman kara oo aad hesho daawayn ka hortag ah ama tallaabooyin ka hortag ah.
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Nature
Nidaamka tafatirka hidda-wadaha waxa uu bartilmaameedsan karaa xayndaab ballaaran oo genome-ka ah iyadoo la kaashanayo enzymes-ka-badan. Nidaamka tafatirka hidda-wadaha waxa uu bartilmaameedsan karaa xayndaab ballaaran oo genome-ka ah iyadoo la kaashanayo enzymes-ka-badan.
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TechCrunch
CRISPR, awoodda kacaanka ah ee lagu dhufto oo lagu beddelo hiddo-wadaha saxda ah ee maqas u eg, ayaa caan ku ahaa dhowrkii sano ee la soo dhaafay waxaana guud ahaan loo arkaa saaxir keli ah oo tafatirka hiddo-wadaha casriga ah. Si kastaba ha ahaatee, ma aha nidaam kaamil ah, mararka qaarkood lagu gooyo meel khaldan, oo aan u shaqeyn sidii loogu talagalay iyo ka tago saynisyahano madaxa xoqan. […]
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CNN
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a16z
Wararka iyo isbeddellada la daboolay toddobaadkan -- dhammaan ku saabsan siyaasaddii ugu dambeysay iyo ficil ahaan saameynta CRISPR -- waxaa ka mid ah:
* Sharciga California ee u baahan calaamado loogu talagalay xirmooyinka wax-ku-tafatirka (oo aan weli jirin)
* Isbahaysiga (oo ay ku jiraan 13 ka mid ah shirkadaha ugu firfircoon ee tafatirka hidda-wadaha ee daaweynta) bayaan mar kale…
* Sharciga California ee u baahan calaamado loogu talagalay xirmooyinka wax-ku-tafatirka (oo aan weli jirin)
* Isbahaysiga (oo ay ku jiraan 13 ka mid ah shirkadaha ugu firfircoon ee tafatirka hidda-wadaha ee daaweynta) bayaan mar kale…
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AAA
Awoodda cusubi waxay siinaysaa bayooloji qalab si ay dib ugu habeeyaan genome-ga bakteeriyada siyaabo badan
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Pub Med
Istaraatiijiyada lagu sharraxay daraasaddan ayaa, mabda' ahaan,, si ballaaran loo waafajin karaa horumarinta unugyada CAR T si looga gudbo qaar ka mid ah caqabadaha suurtagalka ah ee wax soo saarka CAR T-cell. Nidaamkani wuxuu asal ahaan abuuraa CAR T-cell oo leh rheostat shaqeyn isku dhafan.
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banki
Isticmaalka xad-dhaafka ah ee antibiyootiga ayaa u horseedaya masiibo aadanaha.
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Nature
Nidaaminta xulashada bakteeriyada ee dadka microbial-ka adag ayaa fure u ah xakameynta bakteeriyada pathogenic. Nuclear-yada CRISPR waa la qorsheeyey si loo dilo bakteeriyada, laakiin waxay u baahan yihiin nidaam wax-ku-ool ah oo ballaadhan si ay u noqdaan kuwo waxtar leh. Halkan, annagoo isticmaalaya nidaamka wada jirka ee Escherichia coli iyo Salmonella enterica, waxaanu ku tusinaynaa in plasmids ku salaysan nidaamka isku xidhka IncP RK2 loo isticmaali karo sida de
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New saynisyahanka
Tafatirka hidda-wadaha CRISPR waxay u rogi kartaa unugyada baruurta cad inay noqdaan dufan bunni ah oo gubta tamarta, farsamo xaddidaysa korodhka miisaanka jiirarka oo suurtogal ah in loo isticmaalo in lagu daweeyo xanuunada la xidhiidha buurnaanta.
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banki
Saynis yahanada Stanford ayaa sahaminaya in tignoolajiyada tafatirka hiddasidaha loo isticmaali karo la dagaalanka masiibada. Laakiin ilaa hadda, waxay haystaan hal gabal oo ka mid ah xujo weyn.
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Kurzgesagt - Marka la soo koobo
Dhallaanka naqshadeeyay, dhammaadka cudurrada, bini'aadamka hidde ahaan wax laga beddelay oo aan waligood da'in. Waxyaabihii foosha xumaa ee ahaan jiray mala-awaalka cilmiga ayaa si lama filaan ah u noqday...
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Xogta Sayniska
Carl Zimmer, saxafi saynis ah, wuxuu sharxayaa sida uu u shaqeeyo kacaanka cusub ee tafatirka genome-ka ee CRISPR.Zimmer waa qoraaga The New York Times iyo ...
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Laba Daqiiqadood
❤️ Ka soo qaado faa'iidooyin wanaagsan boggayaga Patreon: https://www.patreon.com/TwoMinutePapers Hadalkayga iyo dood-cilmiyeedka buuxa ee shirka NATO (waxaan ka bilaabayaa a...
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NPR
Tani waxay noqon kartaa sanad muhiim u ah farsamada awooda badan ee wax ka beddelka hidda-wadaha CRISPR iyadoo cilmi-baarayaashu ay bilaabeen inay ku tijaabiyaan bukaannada si ay u daweeyaan cudurrada sida kansarka, indho la'aanta iyo cudurka sickle cell.
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Shabakadaha Teknolojiyada
Megatrends waa isbeddellada guud, kuwa abuura oo soo dhaweynaya suuqyo badan iyo horumarinta tignoolajiyada. Isbeddelladani waxay horeba uga jireen adduunkeenna maanta laakiin waxay noqon doonaan kuwo aad uga muhimsan sanadaha soo socda. Halkan waxaan ku iftiiminaynaa saddex megatrends tignoolajiyadeed oo muhiimad weyn u leh mustaqbalkeenna.
