Lithethefatsi tsa botenya: Bakuli ba ka lahleheloa ke karolo ea 15 lekholong ea boima ba 'mele ka ho noa sethethefatsi sena

• Author:
• Lebitso la sengoli

  Quantumrun Ponelopele
• January 8, 2022

Kakaretso ea kutloisiso

Ka bohato bo boholo khahlanong le botenya, moriana o etselitsoeng ho laola lefu la tsoekere o amohetsoe molemong oa ho theola boima ba 'mele. Ka hormone ea maiketsetso ea mala, sethethefatsi sena ha se laole tsoekere ea mali feela empa hape se fokotsa takatso ea lijo ka ho bontša boikutlo ba ho tlala bokong. Leha ho le joalo, litšenyehelo tsa eona tse phahameng, litla-morao tse ka bang teng, le tšusumetso ea li-lobbies tse matla tsa meriana, hammoho le maikutlo a tikoloho le maikutlo a fetohang a bophelo bo botle, li totobatsa ho rarahana ha mokhoa ona o mocha oa ho loantša botenya.

Boemo ba lithethefatsi tsa botenya

US Food and Drug Administration (FDA) e fane ka leseli le letala bakeng sa meriana, eo qalong e neng e sebelisetsoa ho laola lefu la tsoekere, hore e khutlisetsoe ho thusa ho theola boima ba 'mele. Setlhare ke Wegovy, ente ea ngaka ho loants'a bothata bo ntseng bo eketseha ba botenya ka har'a US. Botenya, bo hlalosoang e le ho ba le index ea boima ba 'mele (BMI) ea 30 kapa ho feta, ho hakanngoa hore bo ama motho a le mong ho ba bararo ho pholletsa le naha.

Mochine o susumetsang phello ea Wegovy ke mofuta oa maiketsetso oa homone ea ka maleng ea tlhaho, GLP-1 (glucagon-like peptide 1). Hormone ena e etsa hore manyeme a ntše insulin ka mor'a lijo. Keketseho ea insulin e thusa ho laola tsoekere ea mali, ho netefatsa hore ha e fihle maemong a holimo haholo. Ha hormone ena e kenngoa 'meleng ka ente ea Wegovy, e khona ho tsosa karabelo e tšoanang, e thusa ho laola tsoekere ea mali ka mokhoa o ts'oanang le oa tlhaho oa GLP-1.

Leha ho le joalo, hormone ea GLP-1 e etsa ho fetang feela ho laola insulin. E boetse e buisana le boko, e bontša hore 'mele o khotše, kapa o khotše, ka mor'a ho ja. Ka ho etsisa boikutlo bona ba ho tlala, Wegovy e sebetsa hantle ho thibela takatso ea lijo. Wegovy e bile setlhare sa bobeli sa ho theola boima ba 'mele ho fumana tumello ea FDA ho tloha ka 2014, mme litsebi tsa bophelo bo botle li na le tšepo mabapi le bokhoni ba eona ba ho laola botenya bo behang bophelo kotsing.

Tšusumetso e senyang

Bakuli ba kenyellelitsoeng tekong ea libeke tse 68 bakeng sa lithethefatsi ba tlalehile tahlehelo ea boima ba hoo e ka bang karolo ea 15 lekholong, e phahameng haholo ho feta karolelano ea liphesente tse hlano ho isa ho tse 10 ho tloha meriana e bapisoang. Wegovy e boetse e netefalitsoe hore e bolokehile, e na le litla-morao tse phekolehang habonolo mme li nyamela kamora libeke tse 'maloa. Litla-morao li kenyelletsa ho nyekeloa ke pelo, lets'ollo, le tšilo ea lijo. Dr. Archana Sadhu, mookameli oa lenaneo la lefu la tsoekere la Houston Methodist Hospital, o lumela hore moriana ona o ne o ke ke oa fokotsa lefu la tsoekere feela empa o tla khothalletsa bakuli ho ikoetlisa le ho ja lijo tse phetseng hantle.

Leha ho le joalo, lingaka tse ling ha li nahane hore sethethefatsi sena se hlile se fetola batho. Theko e lebelletsoe ho tšoana le ente e 'ngoe ea Novo Nordisk ea ho theola boima ba 'mele ka chelete e fetang $1,300 USD ka khoeli ntle le inshorense. Inshorense ea naha ea United States ea bophelo bo botle, Medicare, ha e kenyelle liphekolo tsa ho theola boima ba 'mele, e leng se bontšang kamoo botenya bo ntseng bo nkoa e le bothata ba mokhoa oa bophelo ho e-na le bothata ba lefutso.

Meriana e meng ea meriana ea ho theola boima ba 'mele e ntse e tsoela pele. Haeba meriana ena le eona e ka fumana tumello ea FDA, sechaba se tla ba le lisebelisoa tse ngata tse netefalitsoeng tsa ho theola boima ba 'mele ho thibela seoa sa botenya bo atileng Amerika Leboea le lichabeng tse ling tse tsoetseng pele.

Liphello tsa lithethefatsi tsa botenya

Litlamorao tse pharalletseng tsa lithethefatsi tsa botenya li ka kenyelletsa:

• Likhamphani tse ngata tsa pharma tse tsetelang liente le lipilisi tsa bona tsa ho theola boima ba 'mele.
• Tšebeliso e kholo ea lijo tse se nang bophelo bo botle haeba basebelisi ba lithethefatsi tsena ba ikutloa ba e-na le matla a ho ja haholo, ho nka hore lithethefatsi li hlakola boima ba bona ba boima ba 'mele. 
• Lik'hamphani tse ling tsa inshorense tse kenyelletsang lithethefatsi tsa taolo ea boima ba 'mele e le karolo ea kalafo ea lefu la tsoekere le pelo.
• Phaello e fokotsehileng bakeng sa indasteri ea boikoetliso e lokela ho etsa liperesente tsa bareki ho khetha ho nkela boikoetliso ka lithethefatsi tsa ho theola boima ba 'mele. 
• Tsoelo-pele ea lipatlisiso tsa biotechnology, e tsamaisa kutloisiso ea rona ea 'mele oa motho le taolo ea mafu ho isa meeling e mecha.
• Kabo bocha ea lisebelisoa tsa tlhokomelo ea bophelo libakeng tse ling tsa ntlafatso ea sechaba.
• Basebetsi ba phetseng hantle ka nako e telele, ba eketsa tlhahiso le ho fokotsa matsatsi a lahlehetsoeng ke bokuli makaleng a mangata.
• Lits'oants'o tse matla tsa meriana tse lebisang mathateng a lipolotiki ha li leka ho etsa melaoana ea bophelo bo botle e sa tsamaellaneng le lithahasello tsa bona.
• Ho eketseha ha tlhahiso le ho lahloa ha lihlahisoa tsena tsa meriana ho ka beha moroalo o eketsehileng tikolohong, e leng se lebisang tlhokahalong e kholo ea tlhahiso ea meriana e tsitsitseng le maano a ho lahla.

Lipotso tse lokelang ho nahanoa

• Na u ka nahana ho noa lithethefatsi tsa ho theola boima ba 'mele ho laola boima ba hau?
• U nahana hore lithethefatsi tsa ho theola boima ba 'mele li ka fetola tšebeliso ea lijo joang naheng ea heno?