Meriana e ntlafalitsoeng ea psychedelic: Ho fokotsa lithethefatsi ho theha liphekolo tse ntle ka ho fetisisa

• Author:
• Lebitso la sengoli

  Quantumrun Ponelopele
• February 10, 2023

Ha ho etsoa sampole ea lithethefatsi tsa boithabiso, e mong le e mong o itšoara ka tsela e fapaneng ka lebaka la liphatsa tsa lefutso tse fapaneng. Leha ho le joalo, lifeme tsa biotech hona joale li theha liphekolo tsa psychedelic tse etselitsoeng ho shebana le maemo a mangata a bophelo bo botle ba kelello ho latela liphatsa tsa lefutso. 

Boemo bo ntlafalitsoeng ba psychedelics

Lithethefatsi tsa Psychedelic hangata li amahanngoa le tšebeliso e seng molaong, ea ho itlosa bolutu ea lithethefatsi. Ka hona, lipatlisiso tse ngata tsa saense le tsa bongaka ka lintho tsena li tsepamisitse maikutlo liphellong tse mpe tse ka bang teng tsa tšebeliso e mpe. Le hoja ho ntse ho e-na le lintho tse ngata tse sa tsejoeng ka lithethefatsi tsa psychedelic, phuputso ea 2020 e hatisitsoeng koranteng ea Psychological Medicine e bontšitse melemo ea phekolo ea lintho tse kang Ayahuasca, ketamine, LSD, MDMA, kapa psilocybin bakeng sa maemo a kelello a kenyeletsang khatello ea maikutlo le khatello ea kelello ea morao-rao (PTSD). ). Li-psychedelics tsena li bonts'a liphetho tse ts'episang bakeng sa bakuli ba sa kang ba arabela kalafo e tloaelehileng.

Ka lebaka la kamohelo ena e ntseng e eketseha ea litlhare tsa kelello e le phekolo e ka bang teng ea bophelo bo botle ba kelello, linaha tse ’maloa li lumeletse tšebeliso ea tsona ka molao tlas’a litekanyetso tse laoloang. Lifeme tsa biotech le tsona li ntse li nts'etsapele mekhoa ea ho utloisisa psychedelic e 'ngoe le e' ngoe hamolemo, thepa ea eona e ikhethang, le hore na li ka sebetsana le maemo a itseng a kelello joang ho holisa melemo ea nts'etsopele ena. 

Ho ea ka phuputso ea 2017 e hatisitsoeng koranteng ea Neuroscience & Biobehavioral Reviews, lithethefatsi tsa psychedelic, tse kang ketamine, hangata li fumanoe li fokotsa mehopolo ea ho ipolaea ho bakuli ba ipolaeang ka tšohanyetso. Psilocybin, hangata ka tekanyetso e le 'ngoe, e baka litlamorao tsa nako e telele tsa antidepressant ho bakuli ba sa arabeleng kalafong e' ngoe, ho latela Biological Psychiatry. Liphuputso tsena li fana ka maikutlo a hore lithethefatsi tse ntlafalitsoeng bakeng sa liphatsa tsa lefutso le maemo a itseng li ka sebetsa ka nako e telele.

Tšusumetso e senyang

Ka 2021, New York-based Mind Medicine (MindMed) e phatlalalitse merero ea eona ea ho nts'etsapele kalafo ea MDMA bakeng sa matšoenyeho a sechaba le autism spectrum disorder (ASD). Khamphani e ntse e haha ​​​​photefolio ea nts'etsopele ea lithethefatsi ea liphekolo tse ncha tse thehiloeng linthong tsa psychedelic, ho kenyelletsa psilocybin, LSD, MDMA, DMT, le derivative ea ibogaine 18-MC. MindMed e re e batla ho fumana liphekolo tse sebetsanang le bokhoba le mafu a kelello. 

Hajoale ha ho na liphekolo tse lumelletsoeng bakeng sa matšoao a mantlha a ASD, e totobatsang tlhoko e kholo e sa fihlellehang ea liphekolo tse ncha sebakeng sena. Litsenyehelo tsa moruo tsa ASD naheng ea Amerika li lebelletsoe ho fihla ho $461 bilione ka 2025, ho latela MindMed. Ho sa le joalo, karolo ea 12 lekholong ea baahi ka kakaretso e ba le Bothata ba ho Tšoenyeha ka Sechaba ka nako e itseng bophelong ba bona, ho ea ka Setsi sa Sechaba sa Bophelo bo Botle ba Kelello, se hatisa tlhokahalo ea mehato e eketsehileng.

Ka 2022, ATAI Life Sciences e thehiloeng Jeremane e phatlalalitse hore e entse tsoelo-pele e kholo ho nts'etsopele ea phekolo ea bophelo bo botle ba kelello ka lithethefatsi tsa psychedelic. E 'ngoe ea lintlafatso tsena ke COMP360 psilocybin therapy bakeng sa batho ba nang le khatello ea maikutlo e hananang le kalafo. Ho feta moo, k'hamphani e shebile ho rera hape PCN-101 (karolo ea ketamine) e le moriana o sebetsang ka potlako o ka nkoang hae. Ho fihlela joale, liphuputso tsena li bontša hore ho tla ba le phokotso e potlakileng ea matšoao a ho tepella maikutlo nakong ea hora e le 'ngoe ka mor'a tsamaiso,' me e ka nka matsatsi a supileng.

ATAI e boetse e nts'etsapele liphekolo tsa PTSD e sebelisa li-derivatives tsa MDMA. Ho feta moo, motlatsi oa k'hamphani, Revixla Life Sciences, o ithuta kamoo Salvinorin A, motsoako oa tlhaho oa psychedelic, a ka phekolang mafu a sa tšoaneng a bophelo bo botle ba kelello. ATAI e se e qalile liteko tsa eona tse 'maloa tsa bongaka ka 2022.

Litlamorao tsa optimized psychedelics

Litlamorao tse pharalletseng tsa li-psychedelics tse ntlafalitsoeng li ka kenyelletsa: 

• Lits'ebetso tsa biotech li ntse li shebana le 'maraka oa kalafo ea lithethefatsi tsa psychedelic, li sebelisana le li-biotech le litsi tsa lipatlisiso.
• Kamohelo e eketsehileng ea lithethefatsi tsa ho ithabisa e le liphekolo tse molaong, ho fokotsa sekhobo se amanang le tsona.
• Indasteri ea lithethefatsi ea psychedelic e ntse e hola ka potlako ho theosa le lilemo tsa 2020, e tsamaisoang haholo ke mebaraka e ntlafalitsoeng ea lithethefatsi le bophelo bo botle.
• Mebuso e shebileng hore na lithuto le liteko tsa psychedelics li ntse li etsoa joang ho netefatsa hore li lula li le molaong le tsa boitšoaro. Ho ipapisitsoe le liphetho, ho ka fetisoa molao o lumellang ho feta ho lumella tšebeliso ea lithethefatsi tse joalo libakeng tse laoloang kapa ka litekanyetso tse lekanyelitsoeng.
• Ho fifala ha moeli pakeng tsa tšebeliso ea lithethefatsi bakeng sa boithabiso le meriana, e leng se ka bakang ho fetella le ho feta tekano.

Lipotso tseo u ka fanang ka maikutlo ho tsona

• Ke joang hape indasteri ea lithethefatsi ea psychedelic e tla rua molemo 'marakeng o ntlafalitsoeng oa lithethefatsi?
• Haeba u lekile litlhare tsa psychedelic tse thehiloeng ho lithethefatsi, li atlehile hakae?