Ukulawula inzalo kwabesilisa: Amaphilisi okuvimbela inzalo angewona amahomoni amadoda

• About the Author:
• Igama lomlobi

  I-Quantumrun Foresight
• Mashi 15, 2023

Imithi yokuvimbela inzalo yama-hormone ihlotshaniswa nemiphumela engemihle efana nokuzuza isisindo, ukucindezeleka, namazinga aphezulu e-cholesterol. Kodwa-ke, umuthi omusha wokuvimbela inzalo wesilisa ongewona ama-hormone ubonise ukusebenza kahle ekwehliseni inani lesidoda kumagundane ngaphandle kwemiphumela emibi ebonakalayo. Lokhu kutholakala kungase kube intuthuko ethembisayo ekuvimbeleni inzalo, okuhlinzeka ngenye indlela kubantu abangakwazi noma abangathandi ukungazisebenzisi izindlela zokuvimbela inzalo.

Umongo wokulawulwa kokuzalwa kwabesilisa

Ngo-2022, abacwaningi eNyuvesi yaseMinnesota bakha iphilisi elisha lokuvimbela inzalo labesilisa elingelona amahomoni elinganikeza enye indlela ethembisayo ezindleleni ezikhona zokuvimbela inzalo. Umuthi uqondise kuphrotheni i-RAR-alpha emzimbeni wesilisa, esebenzisana ne-retinoic acid ukuvumelanisa umjikelezo we-spermatogenic. Inhlanganisela, ebizwa nge-YCT529, yathuthukiswa kusetshenziswa imodeli yekhompuyutha evumela abacwaningi ukuthi bavimbe ngokunembile isenzo sephrotheni ngaphandle kokuphazamisa ama-molecule ahlobene.

Ocwaningweni olwenziwa ngamagundane abesilisa, abacwaningi bathola ukuthi ukuwondla inhlanganisela kubangele izinga lokusebenza ngamaphesenti angama-99 ekuvimbeleni ukukhulelwa ngesikhathi sokuhlolwa kokukhwelana. Amagundane akwazile ukumithisa abesifazane emasontweni amane kuya kwayisithupha ngemva kokukhishwa ephilisini, futhi akukho miphumela emibi ephawulekayo eyabonwa. Abacwaningi babambisene ne-YouChoice ukuze benze izivivinyo zabantu, okuhlelwe ukuthi ziqale ngasekupheleni kwalo nyaka. Uma kuphumelele, iphilisi kulindeleke ukuthi lifike emakethe ngo-2027.

Nakuba iphilisi elisha linamandla okuba uhlobo olusebenzayo lokuvimbela inzalo kwabesilisa, kusenokukhathazeka ngokuthi amadoda angalisebenzisa yini. Amazinga e-vasectomy e-US aphansi, futhi inqubo yokuhlanganisa ishubhu yabesifazane ehlaselayo isavame kakhulu. Ukwengeza, kusasele imibuzo mayelana nokuthi bekuzokwenzekani uma amadoda eyeka ukuphuza iphilisi, okushiya abesifazane bebhekana nemiphumela yokukhulelwa okungahlosiwe. Ngaphandle kwalokhu kukhathazeka, ukwenza iphilisi lokuvimbela inzalo labesilisa elingewona amahomoni kunganikeza abantu inketho entsha nesebenzayo yokulawula inzalo.

Umthelela ophazamisayo 

Ukutholakala kwengxube enkulu yezinketho zokuvimbela inzalo kokubili kwabesilisa nabesifazane kunganciphisa kakhulu izinga lokukhulelwa okungahleliwe, okungaba nemiphumela emikhulu yezezimali neyomphakathi. Lokhu kuyiqiniso ikakhulukazi ezifundeni lapho ukufinyelela ekulawuleni inzalo kukhawulelwe, njengoba ukunikeza ukukhetha okwengeziwe kungathuthukisa amathuba okuthi abantu bathole indlela esebenza kahle kubo. Ngaphezu kwalokho, uma kuqhathaniswa nezinketho zokuhlinza, amaphilisi okuvimbela inzalo avame ukuthengeka futhi afinyeleleke kuhlu olubanzi lwabantu ngabanye, okuwenza abe yisinqumo esidumile. 

Kodwa-ke, kubalulekile ukuqaphela ukuthi ngisho nezindlela ezihlukahlukene zokuvimbela inzalo, izinga lokuphumelela liyoba nenkulumo-mpikiswano kuze kube yilapho ukusetshenziswa kwazo sekujwayelekile. Ukusebenza kwezindlela zokuvimbela inzalo kuncike ekusetshenzisweni okungaguquguquki nokufanelekile, futhi kusenezici eziningi zenhlalo, amasiko, nezomnotho ezingaba nomthelela ekufinyeleleni nasekusetshenzisweni njalo. Isibonelo, abanye abantu bangase bazizwe bengakhululekile ukuxoxa ngocansi nokuvimbela inzalo nomhlinzeki wabo wezempilo (ikakhulukazi phakathi kwabesilisa), kuyilapho abanye bengase bangakwazi ukufinyelela ukunakekelwa kwekhwalithi ephezulu, okuthengekayo. Ngaphezu kwalokho, ukuqamba amanga ngokuphuza iphilisi noma ukudebesela ekusebenziseni izinto zokuvimbela inzalo kungandisa ubungozi bokukhulelwa okungahleliwe, okuholela emiphumeleni emibi yezempilo neminye imiphumela. Noma kunjalo, ukunikeza abesilisa izinketho ngaphandle kwe-vasectomi kungase kukhuthaze ukuxhumana okukhululekile phakathi kwemibhangqwana efuna ukunquma indlela yokuvimbela inzalo esebenza kangcono kubo. 

Imithelela yokulawulwa kokuzalwa kwabesilisa

Imithelela ebanzi yokulawulwa kokuzalwa kwabesilisa ingase ihlanganise:

• Impilo engcono yabesifazane njengoba beyeka ukuvimbela inzalo okungamahomoni okungaba nemiphumela emibi kakhulu.
• Umthwalo owehlisiwe ezinhlelweni zokunakekelwa kwezingane okungebona abazali bazo kanye namakhaya ezintandane.
• Ikhono elikhulu labesilisa lokuzibophezela ngempilo yabo yokuzala, okuholela ekusabalaleni ngokulinganayo komthwalo wokuvimbela inzalo.
• Izinguquko ekuziphatheni kocansi, okwenza amadoda abe nesibopho esithe xaxa ngokuvimbela inzalo futhi okungenzeka kuholele ekuhlanganeni kocansi okungavamile.
• Ukuncipha kwenani lokukhulelwa okungahlosiwe kanye nokuncipha kwesidingo sezinsizakalo zokuhushula izisu.
• Ukutholakala okukhulu kanye nokusetshenziswa kwamaphilisi okulawula inzalo kwabesilisa okunciphisa ukukhula kwenani labantu, ikakhulukazi emazweni asathuthuka.
• Ukuthuthukiswa nokusatshalaliswa kwamaphilisi okulawula inzalo kwabesilisa kuba udaba lwepolitiki, nezinkulumo mpikiswano mayelana noxhaso lwezimali, ukufinyelela, kanye nokulawulwa.
• Intuthuko kubuchwepheshe bokuvimbela inzalo kanye namathuba amasha ocwaningo lwesayensi nemisebenzi ngaphakathi komkhakha.
• Ukukhulelwa okungahlosiwe okumbalwa okunciphisa ubunzima ezinsizeni futhi kunciphisa umthelela wemvelo wokukhula kwabantu.

Imibuzo okufanele icatshangelwe

• Ucabanga ukuthi amaphesenti amakhulu abantu besilisa azowadla amaphilisi?
• Ngabe ucabanga ukuthi abantu besifazane bayoke bayeke ukuphuza amaphilisi futhi bathembe amadoda ukuthi yiwona azoba nesandla ekuvimbeleni ukukhulelwa?