Pehea e noho ai ka lolo o kahi SuperAger i kēlā ʻoi?

ʻAʻole i lawe mau ʻia ka maʻi o Alzheimer i ka lolo, wahi a nā kānaka ʻepekema ma Northwestern's Cognitive Neurology a me Alzheimer's Disease Center (CNADC). 

Ua nānā ka poʻe ʻepekema i ka lolo o ʻewalu mau 'SuperAgers' i ʻoi aku ma mua o kanaiwa mau makahiki, ʻoi aku ka maikaʻi o ka lolo, a ua ʻike i ka hapa nui o lākou i loaʻa i nā maʻi maʻi o Alzheimer. ʻO kēia ka hopena i ka make ʻana o nā neurons, akā ʻaʻole i ʻike ʻia ka pōʻino i nā cell lolo o kēia mau SuperAgers, ka mea i loaʻa i nā hopena hōʻike hoʻomanaʻo maikaʻi loa.

Ua hōʻike ʻo Changiz Geula, ke kaukaʻi o Cognitive Neurology ma ke kikowaena neurology, i ka hopena o ka honua ma ka Society for Neuroscience 2016 Annual Conference. Ua ʻike kāna hui ʻaʻole pale ʻia nā keʻena o kekahi poʻe ʻelemakule i nā ʻōpala ʻawaʻawa a me nā kuʻi, ka mea maʻamau e make ai ke kelepona i ka hippocampus a me nā wahi ʻē aʻe o ka lolo e mālama i ka hana cognitive.  

"Ke noiʻi ikaika nei mākou i nā kumu psychosocial, biological a me genetic e pili ana me SuperAging. I kēia manawa, ua ʻike mākou he ʻoi aku ka mānoanoa o ka poʻe SuperAger a me nā neurons Von Economo hou aʻe,” wahi a Emily Rogalski, Luna Hoʻokele o Neuroimaging ma CNADC.  

Nā neurons Von Economo  a i ʻole 'Spindle neurons' he papa kikoʻī o nā neurons i ʻoi aku ka nui ma mua o nā cell maʻamau a hiki ke kamaʻilio wikiwiki ma waena o ka lolo. Aia kēia mau neurons kūikawā i loko o ka lolo nui o nā ʻano holoholona e like me nā ʻelepani, nā koholā a me kekahi mau ʻano ʻano ʻano monkey a ua hoʻopili ʻia i ka ʻike pilikanaka.  

"He ʻoi aku ka lohi o ka atrophy i ka SuperAgers i ka manawa, ʻoi aku ka liʻiliʻi o ka maʻi maʻi Alzheimer a ʻoi aku ka liʻiliʻi o ka APOE E4 gene risk factor. ʻO ka APOE E4 ka moʻo i ʻike ʻia ʻo ia ka hopena nui loa i ka ulu ʻana o Alzheimer," wahi a Rogalski. "Manaʻo mākou e loaʻa koke nā hopena hou e pili ana i nā kumu noʻonoʻo a me nā genetic."