Zochitika zachitukuko cha Crispr tech
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yikidwa mawaya
Mapuloteni a CRISPR omwe amagwiritsidwa ntchito ndi njira yomwe imakulitsa RNA imatha kugwiritsidwa ntchito kuzindikira maselo a khansa
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The New England Journal of Medicine
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futurism
Katswiri wa zamoyo wa ku Russia Denis Rebrikov akuti wapeza mabanja asanu omwe akufuna kuti agwiritse ntchito CRISPR kuwonetsetsa kuti ana awo satengera kusamva kwawo.
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MIT Technology Review
Kodi chida champhamvu chosinthira ma gene CRISPR chingathandize kuchiza matenda? Makampani opanga mankhwala akuthamanga kuti adziwe. Mgwirizano waposachedwa wa $ 300 miliyoni pakati pa Bayer AG ndi kuyambitsa CRISPR Therapeutics-kupanga mankhwala atsopano a matenda a magazi, khungu, ndi matenda a mtima obadwa nawo-ndizisonyezero zaposachedwa kwambiri kuti makampani opanga mankhwala akufunitsitsa kupeza ndi kupanga ...
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Cornell Mbiri
Wofufuza wa Cornell, yemwe ndi mtsogoleri pakupanga mtundu watsopano wa kusintha kwa jini CRISPR, ndi anzake agwiritsa ntchito njira yatsopanoyi kwa nthawi yoyamba m'maselo aumunthu - patsogolo kwambiri pamunda.
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Nature
Maphunziro atatu owonetsa kufufutidwa kwakukulu kwa DNA ndikusinthanso kukulitsa nkhawa zachitetezo pakusintha kosinthika kwa ma genome. Maphunziro atatu owonetsa kufufutidwa kwakukulu kwa DNA ndikusinthanso kukulitsa nkhawa zachitetezo pakusintha kosinthika kwa ma genome.
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Thupi
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yikidwa mawaya
Tessera Therapeutics ikupanga gulu latsopano la okonza majini omwe amatha kulumikiza ndendende ma DNA aatali-chinthu chomwe Crispr sangachite.
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New Scientist
Anthu awiri omwe ali ndi beta thalassemia komanso wina yemwe ali ndi matenda a sickle cell sakufunikanso kuikidwa magazi maselo awo atatha kusinthidwa ndi kubwezeretsedwa m'matupi awo.
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New Atlas
Kupambana kwatsopano kodabwitsa kuchokera kwa asayansi ku ETH Zurich, kwa nthawi yoyamba, kwawonetsa njira yatsopano ya CRISPR yomwe imatha kusintha ma jini ambiri nthawi imodzi, kulola kukonzanso ma cell akuluakulu.
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Singularity Hub
China ikuwona kuphulika mu maphunziro a nyama ozikidwa pa CRISPR ndikukumbatira ukadaulo wosintha ma gene ndi changu chosayerekezeka.
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ARK Kusokoneza
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Nature
Ma genetic otchedwa transposon amanyamula makina a CRISPR omwe nthawi zambiri amagwiritsidwa ntchito motsutsana nawo ndi maselo a bakiteriya. Chododometsa ichi chafotokozedwa tsopano, ndi zotsatira za kafukufuku wa majini. Kusintha kwa DNA motsogozedwa ndi RNA.
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Nature
Machitidwe ochiritsira a CRISPR-Cas amasunga umphumphu wa genomic mwa kuwongolera ma RNAs pakuwonongeka kotengera ma nuclease genetic element, kuphatikiza ma plasmids ndi ma virus. Apa tikufotokoza kusinthika kochititsa chidwi kwa paradigm iyi, momwe ma transposon ngati mabakiteriya a Tn7 adasankha machitidwe a CRISPR-Cas omwe alibe ma nuclease-deficient CRISPR-Cas kuti athandizire kuphatikiza motsogozedwa ndi RNA kwa ma genetic element.
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Singularity Hub
Mfundo yake si kukulitsa mantha a anthu pa chida; m'malo mwake, ndiko kuyang'ana patsogolo pa zoopsa zomwe zingatheke ndikupeza njira zodzitetezera.
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Nature
Dongosolo losintha ma jini limatha kuyang'ana mbali yayikulu ya ma genome mothandizidwa ndi ma enzymes osiyanasiyana. Dongosolo losintha ma jini limatha kuyang'ana mbali yayikulu ya ma genome mothandizidwa ndi ma enzymes osiyanasiyana.
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TechCrunch
CRISPR, kuthekera kosinthira kutulutsa ndikusintha majini molondola ngati scissor, yakula kwambiri m'zaka zingapo zapitazi ndipo imawoneka ngati wizard yoyimilira pakusintha kwamakono kwa majini. Komabe, si dongosolo labwino, nthawi zina kudula pamalo olakwika, osagwira ntchito momwe amafunira ndikusiya asayansi akukanda mitu yawo. […]
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CNN
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a16z
Nkhani ndi zomwe zachitika sabata ino - zonse za mfundo zaposachedwa komanso zomwe zikukhudza CRISPR -- zikuphatikiza:
* Lamulo la ku California lofuna zilembo za zida zodzisinthira (zomwe palibe pano)
* Alliance (kuphatikiza 13 mwamakampani omwe akugwira ntchito kwambiri pakukonza ma gene pazamankhwala) inanenanso…
* Lamulo la ku California lofuna zilembo za zida zodzisinthira (zomwe palibe pano)
* Alliance (kuphatikiza 13 mwamakampani omwe akugwira ntchito kwambiri pakukonza ma gene pazamankhwala) inanenanso…
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AAA
Kuthekera kwatsopano kumapatsa akatswiri asayansi chida chokonzanso ma genome a bakiteriya m'njira zambiri
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Kusintha kwa chimeric antigen receptor surface expression ndi chosinthira chaching'ono cha molekyulu
Pub Med
Njira zomwe zafotokozedwa mu kafukufukuyu zitha kusinthidwa kuti zigwirizane ndi kukula kwa ma cell a CAR T kuti tipewe zovuta zina zomwe zingachitike pakupanga ma cell a CAR T. Dongosololi limapanga CAR T-selo yokhala ndi rheostat yophatikizika yogwira ntchito.
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yikidwa mawaya
Kugwiritsa ntchito mankhwala mopitirira muyeso kukubweretsa tsoka kwa anthu.
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Nature
Kusankhidwa kwa mabakiteriya m'magulu a tizilombo toyambitsa matenda ndikofunika kwambiri kuti tipewe tizilombo toyambitsa matenda. Ma nucleases a CRISPR amatha kupangidwa kuti aphe mabakiteriya, koma amafunikira njira yabwino yoperekera anthu osiyanasiyana kuti ikhale yogwira mtima. Apa, pogwiritsa ntchito Escherichia coli ndi Salmonella enterica co-culture system, tikuwonetsa kuti ma plasmids otengera IncP RK2 conjugative system atha kugwiritsidwa ntchito ngati de.
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New Scientist
Kusintha kwa majini a CRISPR kumatha kusintha maselo oyera amafuta kukhala mafuta abulauni omwe amawotcha mphamvu, njira yomwe imachepetsa kulemera kwa mbewa ndipo itha kugwiritsidwa ntchito pochiza matenda okhudzana ndi kunenepa kwambiri.
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yikidwa mawaya
Asayansi aku Stanford akuwunika ngati ukadaulo wosintha ma gene ungagwiritsidwe ntchito kulimbana ndi miliri. Koma mpaka pano, ali ndi kachidutswa kamodzi kokulirapo.
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Mwachidule - Mwachidule
Opanga makanda, kutha kwa matenda, anthu osinthidwa chibadwa omwe samakalamba. Zinthu zonyansa zomwe kale zinali zopeka za sayansi zayamba kuchitika mwadzidzidzi ...
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Sayansi mkati
Carl Zimmer, mtolankhani wa sayansi, akufotokoza momwe chida chosinthira ma genome-editing CRISPR chimagwirira ntchito.Zimmer ndi wolemba nyuzipepala ya The New York Times ndi ...
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Mapepala Awiri A Minute
❤️ Tengani zinthu zabwino patsamba lathu la Patreon: https://www.patreon.com/TwoMinutePapers Nkhani yanga ndi zokambirana zonse pamsonkhano wa NATO (ndikuyamba pa ...
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NPR
Ichi chikhoza kukhala chaka chofunikira kwambiri pa njira yamphamvu yosinthira jini ya CRISPR pomwe ofufuza ayamba kuyesa odwala kuti azichiza matenda monga khansa, akhungu ndi chikwakwa.
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Network Networks
Ma Megatrends ndi njira zokulirapo, zomwe zimabzala ndikukumbatira misika yambiri komanso ukadaulo. Zinthu izi zilipo kale m'dziko lathu masiku ano koma zikhala zofunika kwambiri m'zaka zikubwerazi. Apa tikuwunikira ma megatrend atatu aukadaulo omwe angakhale ofunika kwambiri ku tsogolo lathu.
