Crispr tech development trends
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izilungiselelo
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Wired
Amaprotheni e-CRISPR asetshenziswa nenqubo ekhulisa i-RNA angasetshenziswa ukuthola amaseli omdlavuza
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I-New England Journal of Medicine
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Futurism
Russian biologist Denis Rebrikov says he's found five couples who want him to use CRISPR to ensure their offspring do not inherit their deafness.
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Ukubuyekezwa kwe-MIT Technology
Can the powerful gene-editing tool CRISPR help cure diseases? Drug companies are racing to find out. A recently announced $300 million joint venture between Bayer AG and startup CRISPR Therapeutics—to develop new drugs for blood disorders, blindness, and congenital heart disease—is just the latest indication that the pharmaceutical industry is eager to find and develop…
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Cornell Chronicle
Umcwaningi waseCornell, ongumholi ekuthuthukiseni uhlobo olusha lwesistimu ye-CRISPR yokuhlela izakhi zofuzo, kanye nozakwabo basebenzise indlela entsha okokuqala ngqa kumaseli omuntu - intuthuko enkulu emkhakheni.
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Nature
Izifundo ezintathu ezibonisa ukususwa okukhulu kwe-DNA kanye nokuhlelwa kabusha kukhulisa ukukhathazeka kokuphepha mayelana nokuhlelwa kofuzo oluzuzisayo. Izifundo ezintathu ezibonisa ukususwa okukhulu kwe-DNA kanye nokuhlelwa kabusha kukhulisa ukukhathazeka kokuphepha mayelana nokuhlelwa kofuzo oluzuzisayo.
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Umzimba
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Wired
I-Tessera Therapeutics yakha ikilasi elisha labahleli bofuzo abakwazi ukuxhuma ngokuqondile kubude obude be-DNA—into uCrispr angeke akwazi ukuyenza.
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New Scientist
Two people with beta thalassaemia and one with sickle cell disease no longer need blood transfusions after their blood stem cells were gene edited and put back in their bodies
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I-Atlas entsha
Ukuphumelela okusha okumangalisayo okuvela kososayensi e-ETH Zurich, okokuqala ngqa, kubonise indlela entsha ye-CRISPR engashintsha inqwaba yezakhi zofuzo ngesikhathi esisodwa, okuvumela ukuhlelwa kabusha kwamaseli ngezinga elikhulu.
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Ubumbano Hub
I-China ibona ukuqhuma kwezifundo zezilwane ezisekelwe ku-CRISPR futhi yamukela ubuchwepheshe bokuhlela izakhi zofuzo ngentshiseko engenakuqhathaniswa.
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Nature
Izakhi zofuzo eziyiParasitic ezibizwa ngama-transposons zithwala imishini ye-CRISPR evame ukusetshenziswa ngokumelene nazo ngamaseli ebhaktheriya. Le ndida manje isichazwe, nemithelela ocwaningweni lokwelapha ngofuzo. Ukuguqulwa kwe-DNA okuqondiswa yi-RNA.
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Nature
Izinhlelo ezivamile ze-CRISPR–Cas zigcina ubuqotho be-genomic ngokusebenzisa umhlahlandlela we-RNAs wokuwohloka kwezakhi zofuzo ezincike ku-nuclease, okuhlanganisa ama-plasmids namagciwane. Lapha sichaza ukuguquguquka okuphawulekayo kwale paradigm, lapho ama-transposon afana nebhaktheriya e-Tn7 ekhethe ukusebenzisana nezinhlelo ze-CRISPR-Cas ezingenawo amandla e-nuclease ukuze enze ukuhlanganiswa okuqondiswa yi-RNA kwezakhi zofuzo ezihambayo.
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Ubumbano Hub
Iphuzu akukhona ukubhebhethekisa ukwesaba komphakathi ngaleli thuluzi; kunalokho, kuwukubheka kude ezingozini ezingase zibe khona futhi uthole izindlela zokwelapha zokuvimbela noma zokuphikisa.
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Nature
The gene-editing system could target a broad swathe of the genome with the help of versatile enzymes. The gene-editing system could target a broad swathe of the genome with the help of versatile enzymes.
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I-TechCrunch
I-CRISPR, ikhono loguquko lokukhipha nokuguqula izakhi zofuzo ngokunemba okufana nesikelo, liqhume ukuduma eminyakeni embalwa edlule futhi ngokuvamile libonwa njengewizadi ezimele yokuhlela izakhi zofuzo. Kodwa-ke, akulona uhlelo oluphelele, ngezinye izikhathi lisika endaweni engafanele, lingasebenzi njengoba lihlosiwe futhi lishiye ososayensi benwaya amakhanda. […]
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CNN
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a16z
Izindaba namathrendi okukhulunywa ngawo kuleli sonto -- konke mayelana nenqubomgomo yakamuva kanye nokusetshenziswa okusebenzayo kwe-CRISPR -- kuhlanganisa:
* Umthetho wase-California odinga amalebula ezikhithi zokuzihlela (azikho okwamanje)
* I-Alliance (kuhlanganise nezinkampani ezingu-13 ezisebenza kakhulu ekuhlelweni kofuzo kwezokwelapha) isitatimende futhi...
* Umthetho wase-California odinga amalebula ezikhithi zokuzihlela (azikho okwamanje)
* I-Alliance (kuhlanganise nezinkampani ezingu-13 ezisebenza kakhulu ekuhlelweni kofuzo kwezokwelapha) isitatimende futhi...
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I-AAAS
New ability gives biologists tool to rework bacterial genomes in many ways
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I-Pub Med
Isu elichazwe kulolu cwaningo, ngokomgomo, lingashintshwa kabanzi ekuthuthukisweni kwamaseli e-CAR T ukuze kugwenywe esinye sesithiyo esingaba khona sokwenziwa kwe-CAR T-cell. Le sistimu idala i-CAR T-cell ene-rheostat edidiyelwe esebenzayo.
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Wired
Ukusetshenziswa ngokweqile kwama-antibiotic kudala inhlekelele esintwini.
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Nature
Ukulawulwa okukhethiwe kwamabhaktheriya ezindaweni eziyinkimbinkimbi ze-microbial kuyisihluthulelo sokulawula amagciwane e-pathogenic. Ama-nuclease e-CRISPR angahlelwa ukuthi abulale amagciwane, kodwa adinga uhlelo olusebenzayo nolubanzi lokulethwa kwebanga ukuze lusebenze. Lapha, sisebenzisa i-Escherichia coli kanye ne-Salmonella enterica co-culture system, sibonisa ukuthi ama-plasmids asekelwe ohlelweni lokuhlanganisa lwe-IncP RK2 angasetshenziswa njenge- de.
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New Scientist
Ukuhlelwa kofuzo kwe-CRISPR kungashintsha amangqamuzana amafutha amhlophe abe ngamafutha ansundu ashisa amandla, inqubo enciphisa ukuzuza kwesisindo kumagundane futhi engase isetshenziselwe ukwelapha izifo ezihlobene nokukhuluphala.
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Wired
Ososayensi baseStanford bahlola ukuthi ubuchwepheshe bokuhlela izakhi zofuzo bungasetshenziswa yini ukulwa nobhubhane. Kodwa kuze kube manje, banesiqephu esisodwa sephazili esikhudlwana.
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Kurzgesagt - Kafushane
Izingane zomklami, ukuphela kwezifo, abantu abaguqulwe izakhi zofuzo abangagugi. Izinto ezicasulayo obekuyizinganekwane zesayensi sezivele zisenzeka ngokuphazima kweso...
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Isayensi Insider
Carl Zimmer, a science journalist, explains how the revolutionary new genome-editing tool CRISPR works.Zimmer is a columnist for The New York Times and the a...
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Amaphepha Amabili Wemizuzu
❤️ Thatha izinto ezinhle ekhasini lethu le-Patreon: https://www.patreon.com/TwoMinutePapers Inkulumo yami kanye nengxoxo yephaneli ephelele engqungqutheleni ye-NATO (ngiqala ...
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I-NPR
Lona kungaba unyaka obalulekile endleleni enamandla yokuhlela izakhi zofuzo i-CRISPR njengoba abacwaningi beqala ukuyihlola ezigulini ukuze belaphe izifo ezinjengomdlavuza, ubumpumputhe kanye nesifo se-sickle cell.
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Amanethiwekhi Ezobuchwepheshe
Ama-Megatrend angamathrendi amaningi, lawo enza imbewu futhi amukele ukuthuthukiswa kwezimakethe eziningi nobuchwepheshe. Lezi zindlela sezivele zikhona emhlabeni wethu namuhla kodwa zizobaluleka nakakhulu eminyakeni ezayo. Lapha sigqamisa ama-megatrend amathathu ezobuchwepheshe angabaluleka kakhulu ekusaseni lethu.
