Mekhoa ea ntlafatso ea theknoloji ea Crispr
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ka megala
Liprotheine tsa CRISPR tse sebelisoang ka mokhoa o matlafatsang RNA li ka sebelisoa ho bona lisele tsa mofetše
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The New England Journal of Medicine
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Bokamoso
Setsebi sa baeloji sa Lerussia, Denis Rebrikov, o re o fumane banyalani ba bahlano ba batlang hore a sebelise CRISPR ho etsa bonnete ba hore bana ba bona ha ba futsa ho se utloe ha bona litsebeng.
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Tlhahlobo ea MIT Technology
Na sesebelisoa se matla sa ho fetola liphatsa tsa lefutso CRISPR se ka thusa ho phekola mafu? Lik'hamphani tsa lithethefatsi li matha ho fumana. Khoebo e kopaneng ea $ 300 milione e sa tsoa phatlalatsoa pakeng tsa Bayer AG le ho qala CRISPR Therapeutics-ho hlahisa lithethefatsi tse ncha bakeng sa mafu a mali, bofofu le lefu la pelo la congenital-ke sesupo sa morao-rao sa hore indasteri ea meriana e labalabela ho fumana le ho ntlafatsa ...
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Cornell Chronicle
Mofuputsi oa Cornell, eo e leng moetapele oa ho hlahisa mofuta o mocha oa tsamaiso ea CRISPR ea liphatsa tsa lefutso, le basebetsi-'moho ba sebelisitse mokhoa o mocha ka lekhetlo la pele liseleng tsa batho - tsoelo-pele e kholo tšimong.
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Nature
Lithuto tse tharo tse bonts'ang ho hlakoloa ho hoholo ha DNA le ho hlophisoa bocha li phahamisa matšoenyeho a polokeho mabapi le ho hlophisoa ha liphatsa tsa lefutso. Lithuto tse tharo tse bonts'ang ho hlakoloa ho hoholo ha DNA le ho hlophisoa bocha li phahamisa matšoenyeho a polokeho mabapi le ho hlophisoa ha liphatsa tsa lefutso.
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'Mele
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ka megala
Tessera Therapeutics e nts'etsapele sehlopha se secha sa bahlophisi ba liphatsa tsa lefutso ba khonang ho kenya DNA ka nepo - ntho eo Crispr a sa khoneng ho e etsa.
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New Scientist
Batho ba babeli ba nang le beta thalassemia le e mong ea nang le lefu la sickle cell ha ba sa hloka tšelo ea mali ka mor'a hore lisele tsa bona tsa mali li hlophisoe le ho khutlisetsoa 'meleng ea bona.
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New Atlas
Katleho e ncha e makatsang e tsoang ho bo-ramahlale ba ETH Zurich, ka lekhetlo la pele, e bonts'itse mokhoa o mocha oa CRISPR o ka fetolang mefuta e mengata ea liphatsa tsa lefutso ka nako e le 'ngoe, e lumellang hore ho be le ntlafatso e kholo ea lisele.
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Bonngoe Hub
China e bona ho phatloha ha lithuto tsa liphoofolo tse thehiloeng ho CRISPR le ho amohela theknoloji ea ho fetola liphatsa tsa lefutso ka cheseho e ke keng ea lekanngoa.
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Ho koeteloa ha tšireletso ea CRISPR ka liphatsa tsa lefutso tsa boithati ho na le tšepiso ea bongaka
Nature
Liphatsa tsa lefutso tsa parasitic tse bitsoang transposons li na le mochini oa CRISPR oo hangata o sebelisoang khahlanong le bona ke lisele tsa baktheria. Pherekano ena e se e hlalositsoe, e nang le litlamorao ho lipatlisiso tsa liphatsa tsa lefutso. Phetoho ea DNA e tataisoang ke RNA.
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Nature
Sistimi e tloaelehileng ea CRISPR-Cas e boloka bots'epehi ba genomic ka ho sebelisa tataiso ea RNAs bakeng sa ho senyeha ho itšetlehileng ka nuclease ea likarolo tsa liphatsa tsa lefutso, ho kenyeletsoa li-plasmids le livaerase. Mona re hlalosa phetoho e hlokomelehang ea paradigm ena, eo ho eona li-transposons tse kang baktheria tsa Tn7 li khethileng litsamaiso tsa CRISPR-Cas tse haelloang ke nuclease ho susumetsa kopanyo e tataisoang ke RNA ea mobile genetic element.
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Bonngoe Hub
Taba ha se ho hlohlelletsa tšabo ea sechaba ka sesebelisoa; ho e-na le hoo, ke ho talima esale pele likotsi tse ka ’nang tsa e-ba teng le ho fumana liphekolo tsa thibelo kapa mehato ea ho loantša.
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Nature
Sistimi ea ho hlophisa liphatsa tsa lefutso e ka lebisa tlhokomelo e pharaletseng ea liphatsa tsa lefutso ka thuso ea li-enzyme tse feto-fetohang. Sistimi ea ho hlophisa liphatsa tsa lefutso e ka lebisa tlhokomelo e pharaletseng ea liphatsa tsa lefutso ka thuso ea li-enzyme tse feto-fetohang.
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TechCrunch
CRISPR, bokhoni ba phetoho ea ho hula le ho fetola liphatsa tsa lefutso ka nepo e kang ea sekere, e phatlohile ka botumo lilemong tse 'maloa tse fetileng mme ka kakaretso e bonoa e le wizard e ikemetseng ea ho fetola liphatsa tsa lefutso tsa sejoale-joale. Leha ho le joalo, ha se tsamaiso e phethahetseng, ka linako tse ling e itšeha sebakeng se fosahetseng, e sa sebetse joalokaha e reriloe 'me e siea bo-rasaense ba ntse ba ingoaea lihlooho. […]
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CNN
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a16z
Litaba le mekhoa e tlalehiloeng bekeng ena -- tsohle ka leano la morao-rao le moelelo oa ts'ebetso bakeng sa CRISPR -- li kenyelletsa:
* Molao oa California o hlokang lileibole bakeng sa lisebelisoa tsa ho iketsetsa (tse seng li le teng)
* Alliance (ho kenyeletsoa le lik'hamphani tse 13 tse sebetsang ka ho fetesisa ho hlophisa liphatsa tsa lefutso bakeng sa kalafo) polelo e khahlano le…
* Molao oa California o hlokang lileibole bakeng sa lisebelisoa tsa ho iketsetsa (tse seng li le teng)
* Alliance (ho kenyeletsoa le lik'hamphani tse 13 tse sebetsang ka ho fetesisa ho hlophisa liphatsa tsa lefutso bakeng sa kalafo) polelo e khahlano le…
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AAA
Bokhoni bo bocha bo fa litsebi tsa baeloji sesebelisoa sa ho lokisa liphatsa tsa lefutso tsa baktheria ka litsela tse ngata
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Setsi sa Pub
Leano le hlalositsoeng thutong ena, ha e le hantle, le ka feto-fetoha ka bophara ho nts'etsopele ea lisele tsa CAR T ho qoba tse ling tsa tšitiso e ka bang teng ea tlhahiso ea CAR T-cell. Sistimi ena ha e le hantle e theha CAR T-cell e nang le rheostat e sebetsang e kopaneng.
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ka megala
Tšebeliso e feteletseng ea lithibela-mafu e bakela batho tlokotsi.
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Nature
Taolo e khethiloeng ea libaktheria ka bongata bo rarahaneng ba likokoana-hloko ke senotlolo sa ho laola libaktheria tsa pathogenic. Li-nuclease tsa CRISPR li ka hlophisoa hore li bolaee libaktheria, empa li hloka mokhoa o sebetsang hantle le o pharalletseng oa phano ea batho ba bangata hore o atlehe. Mona, re sebelisa Escherichia coli le Salmonella enterica co-culture system, re bontša hore li-plasmids tse thehiloeng ho IncP RK2 conjugative system li ka sebelisoa e le de.
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New Scientist
Ho hlophisoa ha liphatsa tsa lefutso tsa CRISPR ho ka fetola lisele tse tšoeu tsa mafura hore e be mafura a sootho a chesang matla, mokhoa o fokotsang boima ba 'mele ho litoeba mme o ka sebelisoa ho phekola mathata a amanang le botenya.
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ka megala
Bo-rasaense ba Stanford ba ntse ba hlahloba hore na theknoloji ea ho fetola liphatsa tsa lefutso e ka sebelisoa ho loantša mafu a seoa. Empa ho fihlela joale, ba na le karolo e le 'ngoe feela ea puzzle e kholoanyane.
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Ka bokhutšoanyane - Ka Nutshell
Masea a moqapi, ho fela ha mafu, batho ba fetotsoeng liphatsa tsa lefutso ba sa tsofalang. Lintho tse nyarosang tseo pele e neng e le tšōmo ea mahlale li fetoha ka tšohanyetso ...
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Saense ka Hare
Carl Zimmer, moqolotsi oa litaba oa saense, o hlalosa kamoo sesebelisoa se secha sa phetoho ea genome-editing CRISPR se sebetsang kateng.Zimmer ke sengoli sa koranta ea The New York Times le ...
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Lipampiri tse peli tsa metsotso
❤️ Nka lintho tse ntle leqepheng la rona la Patreon: https://www.patreon.com/TwoMinutePapers Puo ea ka le puisano e felletseng ea sehlopha kopanong ea NATO (ke qala ka ...
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NPR
Sena e ka ba selemo sa bohlokoa bakeng sa mokhoa o matla oa ho fetola liphatsa tsa lefutso CRISPR ha bafuputsi ba qala ho e hlahloba ho bakuli ho phekola mafu a kang mofetše, bofofu le lefu la sekele.
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Maqhubu a Theknoloji
Megatrends ke litloaelo tse atileng, tse jalang le ho amohela nts'etsopele ea 'maraka le theknoloji e mengata. Mekhoa ena e se e ntse e le teng lefatšeng la rona kajeno empa e tla ba ea bohlokoa le ho feta lilemong tse tlang. Mona re totobatsa li-megatrends tse tharo tsa theknoloji tse ka bang bohlokoa haholo bokamosong ba rona.
