Qhov tseem ceeb ntawm qhov chaw nyob hauv (T-cell receptor) vaj tse

T-hlwb tau ntev tau lees paub tias yog linchpin ntawm lub cev tiv thaiv kab mob. Kev txheeb xyuas cov khoom uas muaj teeb meem (xws li cov kab mob sib kis los yog cov qog nqaij hlav cancer) nyob ntawm qhov ua kom cov receptors tawg raws li T-cell nto. Hauv lwm lo lus: "Lub ntsiab lus ntawm lub cev tiv thaiv kab mob yog lub peev xwm ntawm T-hlwb kom paub txog cov antigens. "

Thaum kuaj pom muaj kev phom sij, cov cim biochemical raug xa mus tua cov neeg invaders. Muaj T-cells nrog cov active nto receptors feem ntau xav tias yog qhov zoo tagnrho rau lub cev tiv thaiv kab mob. 

Kev tshawb fawb tam sim no hauv molecular imaging thev naus laus zis yog qhov nyuaj rau cov kev xav no txog T-cell thiab nws cov txiaj ntsig. Raws li kev tshawb fawb no, muaj T-hlwb nrog cov activated receptors yuav tsis tseem ceeb li yuav ua li cas thiab qhov twg cov receptors muab tso rau. 

Cov kws tshawb fawb ntawm University of South Wales tau pom tias qhov ua kom T-hlwb 'cov receptors saum npoo tuaj yeem cuam tshuam rau lawv qhov kev faib tawm. Ntawd yog: qhov ntau pawg ntawm cov receptors yog, qhov zoo dua ntawm lub cell muaj kev paub txog cov antigen thiab txhim kho kev tiv thaiv. 

Kev tshawb fawb qhia tias yog tias cov receptors saum npoo tsis nyob rau hauv cov qauv zoo tshaj plaws los kaw rau ntawm cov tshuaj tiv thaiv, tus naj npawb ntawm T-cells tam sim no yuav ua rau tsis muaj qhov sib txawv tiag tiag. Hloov pauv, tsuav yog cov receptors nyob hauv qhov chaw tseem ceeb, lawv tuaj yeem ua tau zoo dua hauv lawv txoj haujlwm khi.

T-cell muab tso rau hauv kev kho mob

Qhov kev paub no yuav pab txhawb kev kho mob yav tom ntej. Cov kws tshawb fawb cia siab tias yuav siv nanotechnology los rov npaj cov receptors raws li T-cells nto rau hauv pawg ua haujlwm zoo dua. Tsis tsuas yog cov receptors 'kev ua haujlwm tau ua kom zoo nrog txoj kev no, tseem muaj peev xwm los nrhiav ntau T-hlwb rau hauv lub pas dej tiv thaiv. Qhov no tuaj yeem ua tiav los ntawm kev rov ua kom cov receptors hauv "shaus" hlwb. 

Kev tshawb nrhiav txoj hauv kev tshiab los txhim kho tib neeg lub cev tiv thaiv kab mob tuaj yeem ua rau muaj kev qhia ntau dua, cov kev kho mob muaj zog uas tsis muaj cov kev mob tshwm sim qee zaum coj los ntawm cov tshuaj tua kab mob lossis tshuaj tiv thaiv kab mob cancer. Hloov qhov chaw ntawm T-cell receptors tej zaum yuav yog thawj kauj ruam los ua kom tiav cov kev tiv thaiv ntuj.