Ukuhlelwa kofuzo kweCrispr/Cas9 kusheshisa ukuzalanisa okukhethiwe embonini yezolimo

Ukuzalanisa okukhethiwe kuyishintshe kakhulu imboni yezolimo phakathi neminyaka. Ngokwesibonelo, i ummbila nezinhlamvu zanamuhla akubukeki njengento eyakwenza lapho ibumba impucuko yokulima yasendulo. Ngenqubo ehamba kancane, okhokho bethu bakwazi ukukhetha izakhi zofuzo ezimbili usosayensi akholelwa ukuthi ziyimbangela yoshintsho esilubonayo kulezi zinhlobo zezilwane.  

Kodwa ubuchwepheshe obusha bufakazele ukufeza inqubo efanayo, konke ngenkathi kusetshenziswa isikhathi esincane nemali. Okungcono nakakhulu, ngeke nje kube lula kodwa imiphumela izoba ngcono! Abalimi bangakhetha ukuthi yiziphi izici abafuna ukuba nazo ezitshalweni zabo noma imfuyo kuhlelo olufana nekhathalogi!  

Indlela yokusebenza: Crispr/Cas9  

Ngawo-1900, kwavela izitshalo eziningi ezintsha ezishintshwe izakhi zofuzo. Nokho, ukutholwa kwakamuva kweCrispr/Cas9 kuwushintsho oluphelele lomdlalo. Ngalolu hlobo lobuchwepheshe, umuntu angakwazi ukukhomba ukulandelana kofuzo okuthile futhi sika futhi unamathisele ukulandelana okusha endaweni. Lokhu kungase kunikeze abalimi ikhono lokukhetha ngokuqondile ukuthi yiziphi izakhi zofuzo abazifunayo ezitshalweni zabo “kukhathalogi” yezimpawu ezingaba khona!  

Awuthandi isici? Isuse! Ufuna lesi sici? Engeza it! Kulula kanjalo, futhi amathuba awapheli. Ezinye zezinguquko ongayenza ukuzivumelanisa ukubekezelela izifo noma isomiso, ukwandisa isivuno, njll.! 

Lokhu kuhluke kanjani kuma-GMO? 

A I-Genetically Modified Organism, noma i-GMO, iwuhlobo lokuguqulwa kwezakhi zofuzo olwaluhilela ukwethulwa kwezakhi zofuzo ezintsha zolunye uhlobo ukuze kuzuzwe izici umuntu azifunayo. Ukuhlelwa kofuzo, ngakolunye uhlangothi, ishintsha i-DNA esivele ikhona ukuze idale into ephilayo enezici ezithile. 

Nakuba umehluko ungase ungabonakali mkhulu, kubalulekile ukuqonda umehluko nokuthi uthinta kanjani uhlobo. Kuningi imibono engemihle kuma-GMO, njengoba bengavamile ukubhekwa ngepositivity ngabathengi abaningi. Ososayensi abafuna ukugunyaza ukuhlelwa kwezakhi zofuzo ze-Crispr/Cas9 ngezinhloso zezolimo bakholelwa ukuthi kubaluleke kakhulu ukuhlukanisa lokhu kokubili ukuze kususwe isigcwagcwa mayelana nokuhlela izitshalo nemfuyo. Amasistimu e-Crispr/Cas9 abheke ukuvele asheshise inqubo yokuzalanisa kwendabuko okukhethekile.  

Kuthiwani ngemfuyo? 

Mhlawumbe umsingathi owusizo nakakhulu walolu hlobo lwenqubo usemfuyweni. Izingulube zaziwa ukuthi zinezifo eziningi ezingakhuphula izinga lokuphuphuma kwesisu futhi ziholele ekufeni kusenesikhathi. Isibonelo, i-Poricine Reproductive and Respiratory Syndrome (PRRS) ibiza abantu baseYurophu cishe amaRandi ayizigidi eziyizinkulungwane ezingu-1.6 njalo ngonyaka.  

Ithimba eliphuma e-Univesity ye-Edinburgh Roslin Institute isebenza ukususa i-CD163 molecule ebandakanyeka endleleni ebangela igciwane le-PRRS. Ukushicilelwa kwabo kwakamuva ku Iphephabhuku le-PLOS Pathogens kukhombisa ukuthi lezi zingulube zingamelana ngempumelelo negciwane.  

Nalapha futhi, amathuba alobu buchwepheshe awapheli. Angasetshenziselwa izindlela eziningi ezahlukene ezinganciphisa izindleko kubalimi futhi zikhuphule izinga lempilo yalezi zilwane.