Utshwala bokwenziwa: Indawo yotshwala engena-hangover

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• Igama lomlobi

  I-Quantumrun Foresight
• Mashi 2, 2022

Isifinyezo sokuqonda

I-Alcarelle, utshwala bokwenziwa, ihlose ukunikeza imiphumela ethokozisayo yotshwala bendabuko ngaphandle kwemiphumela engemihle, efana nama-hangover. Lolu hlobo olusha lotshwala lungaguqula isimo sengqondo somphakathi mayelana nokuphuza, ngokunokwenzeka kwenze kube umsebenzi ovamile, ovamile. Ngaphezu kwalokho, ukwethulwa kotshwala bokwenziwa kuveza izinselelo namathuba, kusukela ekulungisweni kokulawula kanye nokushintshashintsha kwezimakethe kuya ezinzuzweni ezingaba khona zemvelo.

Ingqikithi yotshwala bokwenziwa

I-Alcarelle, eyayibizwa ngokuthi i-alcasynth, ithatha indawo yotshwala eyathuthukiswa nguSolwazi David Nutt, umqondisi we-Neuropsychopharmacology Unit ophikweni lwe-Brain Sciences e-Imperial College London. Umqondo wotshwala bokwenziwa uwukudala utshwala abantu abangabuphuza obunikeza imiphumela evamile yotshwala ngaphandle kokuholela kubathengi babo bakhathazeke ngokuhlushwa i-hangover noma eminye imiphumela emibi yokuphuza utshwala.

Umqondo wokuthatha indawo yotshwala wafika kuProfesa David Nutt ngenkathi ecwaninga imiphumela yotshwala kuma-GABA receptors. Ama-GABA receptors angama-neurotransmitters ahlotshaniswa ne-sedation nokuphumula. Ukuphuza utshwala kulingisa ama-GABA receptors, ngaleyo ndlela kubangele ukuba nesiyezi kanye ne-tipsiness futhi kubangele lokho okuvame ukubizwa ngokuthi i-hangover post-consumption. I-Alcarelle, njengoba ihlongozwa ngu-Nutt, izonikeza yonke imiphumela ephumuzayo yotshwala ngaphandle kokuthi abaphuzayo baphathwe yi-hangover. 

Nakuba ukwakheka kwamakhemikhali athile otshwala bokwenziwa akukabi ulwazi olusesidlangalaleni, kulindeleke ukuthi kuphephe ukuthi kusetshenziswe uma sekutholakala esidlangalaleni. Abanye abacwaningi elabhorethri ye-Nutt baye bazama i-alcarelle, futhi nakuba ingase ingabi mnandi ngendlela eyodwa, ingaxutshwa nolunye uketshezi olufana nejusi yezithelo ukuyinika ukunambitheka okumnandi. Uma i-alcarelle itholakala kabanzi ukuze isetshenziswe, cishe izothengiswa ngamabhodlela nasemathini afana nozakwabo abavamile botshwala ngemva kokuhlanganiswa elabhorethri. Ngaphambi kokukhululwa komphakathi, kuzodinga ukugunyazwa izinhlangano ezilawulayo.

Umthelela ophazamisayo

Utshwala bokwenziwa bungashintsha kakhulu izimo zengqondo zomphakathi mayelana nokuphuza. Ngokususwa kwemiphumela emibi, isigcwagcwa esihambisana nokuphuza ngokweqile singase sinciphe, okuholela ekushintsheni ezinkambisweni zomphakathi, lapho ukuphuza kuba into evamile, umsebenzi wansuku zonke kunokuba impelasonto noma umcimbi okhethekile. Kodwa-ke, lolu shintsho lungase luholele ekwenyukeni kwezindaba zokuthembela, njengoba abantu bangase bakuthole kulula ukuphuza utshwala kaningi ngaphandle kwezithiyo ezingokomzimba ezisheshayo.

Izinkampani ezijwayela ngokushesha futhi zinikeze izinketho zokwenziwa zotshwala zingabamba ingxenye enkulu yemakethe, ikakhulukazi phakathi kwabathengi abancane abavulekele ukuzama imikhiqizo emisha. Kodwa-ke, izindawo zokuphuza utshwala zendabuko kanye nama-distilleries zingabhekana nokwehla kwesidingo semikhiqizo yazo, okuziphoqa ukuthi zivumelane nezimo noma zibe sengozini yokuphelelwa yisikhathi. Ngaphezu kwalokho, amabhizinisi asembonini yokwamukela izihambi, njengamabha nezindawo zokudlela, kungase kudingeke ukuthi acabange kabusha ngokunikela kwawo namasu entengo, njengoba utshwala bokwenziwa bungase bushibhe futhi bukhiqize kalula.

Kohulumeni, ukuvela kotshwala bokwenziwa kungaholela ekwehleni kwezindaba zezempilo ezihlobene notshwala, kwehlise umthwalo ezinhlelweni zokunakekelwa kwempilo. Nokho, kungase kubangele izinselele ezintsha zokulawula. Abenzi benqubomgomo bazodinga ukusungula imihlahlandlela emisha yokukhiqiza, ukuthengiswa, kanye nokusetshenziswa kotshwala bokwenziwa, ukulinganisa izinzuzo ezingaba khona nezingozi zokuthembela okwengeziwe. Ukwengeza, ohulumeni kuzodingeka bacabangele umthelela wezomnotho ezimbonini zotshwala obuvamile kanye nokulahlekelwa kwemisebenzi okungase kube umphumela walolu shintsho.

Imiphumela yotshwala bokwenziwa

Imithelela ebanzi yotshwala bokwenziwa ingase ihlanganise:

• Izinkambu ezintsha ziyadalwa ngaphakathi kwemboni ye-mixology, njengoba i-alcarelle ingaxutshwa nama-flavour ahlukene ukuze inikeze izinhlobo ezintsha zemizwa yokunambitha kubathengi.
• Amaqembu alwa ne-alcarelle asungulwa ukuze amelane nokusatshalaliswa komphakathi nokudayiswa kwe-alcarelle ngenxa yemiphumela yayo emibi engaba khona. Izinhlangano ezithakasela umphakathi zingase futhi zethule imibuzo, imithetho kahulumeni, kanye nokwanda kocwaningo mayelana nokukhiqizwa koketshezi. 
• Imboni yotshwala ibona ukukhula okuvuselelwe njenge-alcarelle (nezinye eziphuma esikhundleni sotshwala) imele umkhiqizo omusha oqondile ongagcwalisa izinketho ezikhona zotshwala emakethe. 
• Ukushintsha kokuncanyelwayo kwabathengi ekubhekiseni utshwala bokwenziwa, okuholela ekwehleni kwesidingo sophuzo oludakayo lwendabuko kanye nokubunjwa kabusha okungenzeka kwemboni yeziphuzo.
• Ukwehla kwesidingo sezolimo sezitshalo ezifana nebhali, ama-hops, namagilebhisi, okunomthelela kubalimi kanye nomkhakha wezolimo.
• Imithethonqubo emisha nezinqubomgomo zentela, ezithinta isimo somthetho kanye nemithombo yemali engenayo yomphakathi.
• Ukukhiqizwa kotshwala bokwenziwa kuba nobungane ngokwemvelo kunezindlela zendabuko, okuholela ekwehleni kokusetshenziswa kwamanzi kanye nokukhiqizwa kukadoti embonini yotshwala.

Imibuzo okufanele icatshangelwe

• Ingabe i-alcarelle kufanele itholakale esidlangalaleni, ucabanga ukuthi abathengi abajwayelekile bazosebenzisa iziphuzo ze-alcarelle?
• Ingabe ukusetshenziswa kwe-alcarelle ezinhlotsheni ezahlukene zeziphuzo kufanele kuvalwe ngenxa yamandla okukhuthaza ukuphuza ngokweqile, ikakhulukazi phakathi kwezidakwa kanye nabantu abasha?